Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL28368169 | 0.89 | LMNA (0.52) | SIGMAR1BCL2L1TSHRCYP2C19KDM4E | |
| SCHEMBL554550 | 0.86 | AOC3 (0.59) | SIGMAR1BCL2L1KCNH2TSHRCHRM1 | |
| Pyridine SCHEMBL28412687 | 0.84 | TAAR1 (0.58) | SIGMAR1KCNH2TSHRCHRM2CHRM1 | |
| SCHEMBL2277966 | 0.81 | SIGMAR1 (0.62) | SIGMAR1BCL2L1KCNH2TSHRAOC3 | |
| SCHEMBL7092468 | 0.79 | SIGMAR1 (0.53) | SIGMAR1KCNH2AOC3CHRNA7CHRM5 | |
| SCHEMBL11440302 | 0.77 | HRH3 (0.53) | SIGMAR1BCL2L1KCNH2TSHRSLC6A2 | |
| SCHEMBL11387795 | 0.77 | BCL2L1 (0.50) | SIGMAR1BCL2L1KCNH2TSHRCHRM1 | |
| SCHEMBL9670561 | 0.76 | SIGMAR1 (0.64) | SIGMAR1KCNH2CHRM2CHRM1SLC6A2 | |
| SCHEMBL14528082 | 0.75 | FDPS (0.62) | SIGMAR1BCL2L1KCNH2CHRM1AOC3 | |
| Maleic Acid SCHEMBL28700882 | 0.75 | TAAR1 (0.52) | TSHRCYP2C19AOC3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773176-B | Chlorpheniramine maleate impurity and preparation method and application thereof | 山西辅仁恒峰药业有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-113956197-A | Preparation method of chlorpheniramine maleate impurity | 艾希尔（深圳）药物研发有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-111138350-B | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-111138350-A | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2020-05-12 | — | — | CN | disclosed |