SCHEMBL28407451

SCHEMBL28407451

Nc1c(O)ccc(CCCl)c1CCCl

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 2/20 0.32
BACE1 P56817 1/20 0.31
ACHE P22303 1/20 0.31
TYR P14679 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19972011 0.80 PRKCI (0.44) PRKCIBACE1ACHETYR
SCHEMBL4174708 0.78 TYR (0.33) TYR
SCHEMBL28898830 0.76 TYR (0.57) ACHETYR
SCHEMBL7770151 0.76 TYR (0.39) TYR
SCHEMBL3685539 0.75 TAAR1 (0.43)
SCHEMBL21878594 0.74 TYR (0.60) ACHETYR
SCHEMBL8724102 0.74 CASP6 (0.38)
SCHEMBL6535376 0.73 AOC1 (0.30)
SCHEMBL4336551 0.72 SMN1; SMN2 (0.41)
SCHEMBL5082011 0.71 ALDH1A1 (0.35) PRKCIACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107835817-B Esters of steroid amides and bis (2-chloroethyl) aminophenoxypropionic acid derivatives 格林尼卡股份公司 2020-04-21 CN disclosed