SCHEMBL6535376

SCHEMBL6535376

CNc1ccc(CCCl)c(CCCl)c1N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596316 0.78 TAAR1 (0.32) AOC1AOC3
SCHEMBL17846673 0.76 APP (0.35)
SCHEMBL10881330 0.74 ALDH1A1 (0.44)
SCHEMBL3838657 0.73 PRKCI (0.34) AOC1AOC3
SCHEMBL28407451 0.73 PRKCI (0.32)
SCHEMBL28120010 0.68
SCHEMBL8724102 0.68 CASP6 (0.38)
SCHEMBL21944103 0.67 TYR (0.41)
SCHEMBL28058874 0.67 PRKCI (0.43)
SCHEMBL4336551 0.66 SMN1; SMN2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041995-A4 TRIALKYL-LOCK-FACILITATED POLYMERIC PRODRUGS OF AMINO-CONTAINING BIOACTIVE AGENTS ENZON INC (US) 2004-10-06 EP disclosed
EP-1041995-A1 TRIALKYL-LOCK-FACILITATED POLYMERIC PRODRUGS OF AMINO-CONTAINING BIOACTIVE AGENTS ENZON, INC. (US) 2000-10-11 EP disclosed
WO-1999033483-A1 TRIALKYL-LOCK-FACILITATED POLYMERIC PRODRUGS OF AMINO-CONTAINING BIOACTIVE AGENTS ENZON, INC. (US) 1999-07-08 WO disclosed