Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409114 | 0.88 | SLC6A3 (0.36) | SLC6A3SLC6A2MAPTMEN1LMNA | |
| SCHEMBL28401560 | 0.77 | NPC1 (0.34) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28412341 | 0.75 | MEN1 (0.32) | MAPTMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL7426060 | 0.71 | ALDH1A1 (0.32) | MEN1LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL6846856 | 0.65 | FBP1 (0.37) | ALDH1A1CNR2L3MBTL1CNR1 | |
| SCHEMBL11715755 | 0.63 | LMNA (0.30) | MAPTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28700917 | 0.60 | CYP1A2 (0.32) | — | |
| SCHEMBL28712291 | 0.58 | KMT2A (0.34) | SLC6A3SLC6A2MAPTMEN1LMNA | |
| SCHEMBL5091273 | 0.58 | ALDH1A1 (0.48) | SLC6A3SLC6A2MAPTMEN1LMNA | |
| SCHEMBL7827008 | 0.57 | PLAU (0.59) | SLC6A3SLC6A2MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101845-B | Preparation method of eltrombopag | 苏州科伦药物研究有限公司 | 2020-05-15 | — | — | CN | disclosed |