Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414541 | 0.88 | SLC6A3 (0.38) | SLC6A3SLC6A2ALDH1A1MAPTLMNA | |
| SCHEMBL28412341 | 0.87 | MEN1 (0.32) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL28401560 | 0.86 | NPC1 (0.34) | ALDH1A1MAPTMEN1KMT2ACNR2 | |
| SCHEMBL6846856 | 0.75 | FBP1 (0.37) | ALDH1A1CNR2L3MBTL1 | |
| SCHEMBL11638785 | 0.65 | KDM4E (0.31) | ALDH1A1MAPTLMNAKMT2AALOX12 | |
| SCHEMBL11715755 | 0.64 | LMNA (0.30) | ALDH1A1MAPTLMNAKMT2AALOX12 | |
| SCHEMBL7426060 | 0.63 | ALDH1A1 (0.32) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL6850656 | 0.61 | CRHBP (0.34) | ALDH1A1TDP1 | |
| SCHEMBL28712291 | 0.59 | KMT2A (0.34) | SLC6A3SLC6A2ALDH1A1MAPTLMNA | |
| SCHEMBL5091273 | 0.58 | ALDH1A1 (0.48) | SLC6A3SLC6A2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101845-B | Preparation method of eltrombopag | 苏州科伦药物研究有限公司 | 2020-05-15 | — | — | CN | disclosed |