SCHEMBL28419366

SCHEMBL28419366

CCC(=C(C)C(=O)O)c1ccccc1CC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 2/20 0.41
HTT P42858 1/20 0.38
FOLH1 Q04609 1/20 0.37
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
F2R P25116 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TSHR P16473 1/20 0.36
SLC6A1 P30531 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
ALOX15 P16050 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ERCC5 P28715 1/20 0.35
FEN1 P39748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345323 0.84 CLCN2 (0.42) CLCN2HTTFOLH1GABRA1GABRB2
SCHEMBL6189630 0.82 ALDH1A1 (0.52) CES2CES1TSHRALDH1A1ERCC5
SCHEMBL5175464 0.78 CLCN2 (0.42) CLCN2HTTF2RTSHRALDH1A1
SCHEMBL4624841 0.78 NR4A1 (0.53) TSHRALDH1A1LMNAALOX15
SCHEMBL5528072 0.78 ESR1 (0.46) CLCN2GABRA1GABRB2CES2CES1
SCHEMBL8860998 0.78 GABRA1 (0.39) CLCN2HTTGABRA1GABRB2F2R
SCHEMBL10586913 0.77 GABRA1 (0.46) CLCN2HTTFOLH1GABRA1GABRB2
SCHEMBL5279624 0.77 CES2 (0.50) CES2CES1L3MBTL1
Oxalic Acid SCHEMBL2035738 0.77 ALDH1A1 (0.47) CLCN2HTTFOLH1GABRA1GABRB2
SCHEMBL7174103 0.77 CES2 (0.50) CES2CES1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107249549-B Cosmetic material 捷鸥化妆品株式会社 2020-06-09 CN disclosed