SCHEMBL345323

SCHEMBL345323

CCC(=C(C(=O)O)C(=O)O)c1ccccc1CC

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB2 P47870 2/20 0.42
HTT P42858 1/20 0.39
FOLH1 Q04609 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
TSHR P16473 1/20 0.37
F2R P25116 1/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
KAT6A Q92794 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15913630 0.84 GABRA1 (0.42) CLCN2GABRA1GABRB2HTTTSHR
SCHEMBL28419366 0.84 CLCN2 (0.41) CLCN2GABRA1GABRB2HTTFOLH1
SCHEMBL4075524 0.81 ALDH1A1 (0.41) CLCN2HTTTSHRF2RALDH1A1
SCHEMBL5175464 0.80 CLCN2 (0.42) CLCN2HTTTSHRF2RALDH1A1
SCHEMBL5528072 0.79 ESR1 (0.46) CLCN2GABRA1GABRB2CES2CES1
SCHEMBL10586913 0.79 GABRA1 (0.46) CLCN2GABRA1GABRB2HTTFOLH1
SCHEMBL1286085 0.78 CES2 (0.41) CLCN2GABRA1GABRB2HTTCES2
SCHEMBL3968516 0.77 HSP90AB1 (0.46) HTTCES2TSHRALDH1A1ALOX15
SCHEMBL3969827 0.77 POLB (0.40) ALDH1A1ERCC5FEN1CYP2C9
SCHEMBL8853098 0.76 POLB (0.48) CLCN2GABRA1GABRB2HTTFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof EVOLVED BY NATURE INC (US) 2026-01-15 US claimed
US-11878070-B2 Silk-based moisturizer compositions and methods thereof EVOLVED BY NATURE, INC. (US) 2024-01-23 US claimed
EP-3288528-A1 SILK-BASED MOISTURIZER COMPOSITIONS AND METHODS THEREOF Silk Therapeutics Inc. (US) 2018-03-07 EP claimed
WO-2016176633-A1 SILK-BASED MOISTURIZER COMPOSITIONS AND METHODS THEREOF Silk Therapeutics, Inc. (US) 2016-11-03 WO claimed
US-9402793-B2 Use of UV-filters to stabilize resveratrol in topical cosmetic compositions DSM IP ASSETS B.V. (NL) 2016-08-02 US claimed
US-20130324616-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP ASSETS B.V. (NL) 2013-12-05 US claimed
US-20130315848-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2013-11-28 US claimed
EP-2642973-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP Assets B.V. (NL) 2013-10-02 EP claimed
WO-2012069362-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2012-05-31 WO claimed
WO-2004062635-A1 COMPOSITIONS FOR SKIN LIGHTENING COMPRISING BIS-PANTOYL-CYSTAMINE DSM IP ASSETS B.V. (NL) 2004-07-29 WO claimed
US-20260137613-A1 MANUFACTURE, ISOLATION, PURIFICATION, AND USES OF SMALL PARTICLE SIZE CELLULOSE PARTICLES AND COMPOSITIONS RENMATIX INC (US) 2026-05-21 US disclosed
US-20260068887-A1 XANTHENE DYE COMBINATIONS FOR ENHANCED BACTERIAL, YEAST, AND FUNGAL MICROBIAL CONTROL ICHOR MICROBIAL SOLUTIONS INC (US) 2026-03-12 US disclosed
US-12558303-B2 Manufacture, isolation, purification, and uses of small particle size cellulose particles and compositions RENMATIX, INC. (US) 2026-02-24 US disclosed
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof EVOLVED BY NATURE INC (US) 2026-01-15 US disclosed
US-12447122-B2 Silk-based moisturizer compositions and methods thereof EVOLVED BY NATURE, INC. (US) 2025-10-21 US disclosed
WO-2000023044-A1 UV PROTECTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-04-27 WO disclosed
EP-0736070-B1 PROCESS FOR MAKING A NON-AQUEOUS DISPERSION OF A COOPER PHTHALOCYANINE ZENECA LTD (GB) 1999-02-24 EP disclosed
US-5753022-A FOR PREPARING NONAQUEOUS DISPERSION OF COPPER PHTHALOCYANINE BY MILLING IN A HIGH BOILING LIQUID IN THE PRESENCE OF A POLYESTER AMINE OR POLYESTERAMMONIUM SALT SALT AND A FLUIDIZING AGENT ZENECA LIMITED (GB) 1998-05-19 US disclosed
EP-0736070-A1 PROCESS FOR MAKING A NON-AQUEOUS DISPERSION OF A COOPER PHTHALOCYANINE ZENECA LIMITED (GB) 1996-10-09 EP disclosed
WO-1995017473-A1 PROCESS FOR MAKING A NON-AQUEOUS DISPERSION OF A COOPER PHTHALOCYANINE ZENECA LIMITED (GB) 1995-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068887-A1 XANTHENE DYE COMBINATIONS FOR ENHANCED BACTERIAL, YEAST, AND FUNGAL MICROBIAL CONTROL TYR, PPOX, TH CLCN2 4409/4885GABRA1 4743/4885GABRB2 4304/4885
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof CUTA, CD44, F12 CLCN2 3320/4885GABRA1 4096/4885GABRB2 4446/4885
US-12558303-B2 Manufacture, isolation, purification, and uses of small particle size cellulose particles and compositions CUTA, COL2A1, SAMM50 CLCN2 3499/4885GABRA1 4488/4885GABRB2 4645/4885
US-20260137613-A1 MANUFACTURE, ISOLATION, PURIFICATION, AND USES OF SMALL PARTICLE SIZE CELLULOSE PARTICLES AND COMPOSITIONS CUTA, COL2A1, COL1A1 CLCN2 3002/4885GABRA1 4592/4885GABRB2 4676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.