SCHEMBL28423950

SCHEMBL28423950

CC1(c2ccccc2)O[Si](C)(C)CCC1O[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28577296 0.74 KDM1A (0.41)
SCHEMBL28558685 0.63 CHRM2 (0.36)
SCHEMBL28362728 0.62
SCHEMBL6573456 0.62 TSHR (0.35)
SCHEMBL3263252 0.62 HSD11B1 (0.36)
SCHEMBL2048189 0.61 OPRM1 (0.33)
SCHEMBL182247 0.60 OPRM1 (0.35)
SCHEMBL28238211 0.60 CHRNB2 (0.31)
SCHEMBL18126 0.59 HSD11B1 (0.36)
SCHEMBL2232620 0.59 OPRM1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109431963-B Transparent oil bead suspension essence water and preparation method thereof 蓓悠清(广东)健康科技有限公司 2021-10-26 CN claimed
CN-111433256-B Organic group-modified silicone resin, method for producing same, and cosmetic 信越化学工业株式会社 2022-08-23 CN disclosed
CN-108623809-B Organic group-modified silicone resin, method for producing same, and cosmetic 信越化学工业株式会社 2022-03-15 CN disclosed
CN-109414396-B Cosmetic preparation 信越化学工业株式会社 2021-10-29 CN disclosed
CN-109431963-B Transparent oil bead suspension essence water and preparation method thereof 蓓悠清(广东)健康科技有限公司 2021-10-26 CN disclosed
CN-111433256-A Organic group-modified silicone resin, method for producing same, and cosmetic 信越化学工业株式会社 2020-07-17 CN disclosed