Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28442664 | 0.88 | EGLN1 (0.50) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30345507 | 0.88 | EGLN1 (0.50) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30345442 | 0.87 | EGLN1 (0.47) | EGLN1DEGS1EGLN3NPC1RAB9A | |
| SCHEMBL28452694 | 0.87 | EGLN1 (0.47) | EGLN1DEGS1EGLN3NPC1RAB9A | |
| SCHEMBL30345412 | 0.85 | ITGB3 (0.53) | MEN1NPC1RAB9AKMT2AHDAC1 | |
| SCHEMBL28439104 | 0.85 | ITGB3 (0.53) | MEN1NPC1RAB9AKMT2AHDAC1 | |
| SCHEMBL28445193 | 0.84 | KDM4E (0.48) | EGLN1DEGS1MEN1NPC1RAB9A | |
| SCHEMBL30345425 | 0.84 | KDM4E (0.48) | EGLN1DEGS1MEN1NPC1RAB9A | |
| SCHEMBL28446135 | 0.84 | HDAC3 (0.53) | EGLN1EGLN3RAB9AFTOKDM5B | |
| SCHEMBL30345445 | 0.84 | HDAC3 (0.53) | EGLN1EGLN3RAB9AFTOKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | claimed |
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | disclosed |