Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28442664 | 1.00 | EGLN1 (0.50) | EGLN1MMP1THRATHRBNPC1 | |
| SCHEMBL28439104 | 0.89 | ITGB3 (0.53) | NPC1RAB9AMEN1CASP3KMT2A | |
| SCHEMBL30345412 | 0.89 | ITGB3 (0.53) | NPC1RAB9AMEN1CASP3KMT2A | |
| SCHEMBL28445193 | 0.88 | KDM4E (0.48) | EGLN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30345425 | 0.88 | KDM4E (0.48) | EGLN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28441539 | 0.88 | DGAT1 (0.49) | EGLN1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL28449008 | 0.86 | EGLN1 (0.48) | EGLN1THRATHRBGAABBOX1 | |
| SCHEMBL30345516 | 0.86 | EGLN1 (0.48) | EGLN1THRATHRBGAABBOX1 | |
| SCHEMBL28897243 | 0.85 | EGLN1 (0.50) | EGLN1THRATHRBRAB9AGAA | |
| SCHEMBL28452694 | 0.84 | EGLN1 (0.47) | EGLN1NPC1RAB9AKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | disclosed |