Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345412 | 1.00 | ITGB3 (0.53) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28442664 | 0.89 | EGLN1 (0.50) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL30345507 | 0.89 | EGLN1 (0.50) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL30345425 | 0.85 | KDM4E (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28445193 | 0.85 | KDM4E (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28441539 | 0.85 | DGAT1 (0.49) | RAB9ANPC1MEN1KMT2AHDAC1 | |
| SCHEMBL28452694 | 0.82 | EGLN1 (0.47) | RAB9ANPC1SMN1; SMN2KMT2ARXFP1 | |
| SCHEMBL30345442 | 0.82 | EGLN1 (0.47) | RAB9ANPC1SMN1; SMN2KMT2ARXFP1 | |
| SCHEMBL1222408 | 0.80 | ITGB3 (0.73) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28449008 | 0.78 | EGLN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | claimed |
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | disclosed |