Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGFR | P43088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422923 | 0.86 | CASP3 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL2820048 | 0.85 | MMP13 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL2823483 | 0.82 | KDM4E (0.32) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2823352 | 0.74 | PDE2A (0.31) | — | |
| SCHEMBL2819656 | 0.74 | ALDH1A1 (0.36) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2819998 | 0.73 | P2RX7 (0.32) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2820325 | 0.72 | TSHR (0.40) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL2821980 | 0.72 | RAB9A (0.35) | — | |
| SCHEMBL2820985 | 0.71 | MMP13 (0.34) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL2822078 | 0.71 | MMP13 (0.37) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |