Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305145 | 0.89 | TSHR (0.48) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL197202 | 0.82 | MEN1 (0.62) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL1304998 | 0.82 | LMNA (0.50) | CYP1A2TSHRLMNAALDH1A1 | |
| SCHEMBL2154715 | 0.81 | L3MBTL1 (0.42) | NPC1RAB9AMEN1KMT2AHSD11B1 | |
| SCHEMBL2974451 | 0.79 | POLB (0.59) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| Carbon Monoxide SCHEMBL10627118 | 0.78 | POLB (0.59) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL28443581 | 0.76 | CES2 (0.50) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5049965 | 0.75 | KIF11 (0.56) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| Formic Acid SCHEMBL31540153 | 0.74 | POLB (0.60) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL2154599 | 0.73 | TSHR (0.48) | RAB9AMEN1KMT2ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574564-A | Fluoroalkyl-substituted furyl diphosphine oxygen compound and preparation method thereof | 南京工业大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-111560038-A | Fluoroalkyl-substituted furyl monophosphine oxide compound and preparation method thereof | 南京工业大学 | 2020-08-21 | — | — | CN | disclosed |