Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628431 | 0.71 | NOTUM (0.38) | PGRNOTUMKDM1AMAOBTAAR1 | |
| SCHEMBL4603856 | 0.67 | ALOX5 (0.38) | PGRNOTUMTAAR1TSHRNPC1 | |
| SCHEMBL5152974 | 0.65 | HTT (0.30) | — | |
| SCHEMBL21091939 | 0.64 | PGR (0.38) | PGRNOTUMIDO1MEN1KMT2A | |
| SCHEMBL10410660 | 0.63 | ALDH1A1 (0.37) | NOTUMKDM1AMAOBTDO2DHFR | |
| SCHEMBL28874371 | 0.61 | HTT (0.34) | KDM1AMAOBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10800694 | 0.60 | MAOA (0.38) | TSHRNPC1MAPTUSP7MEN1 | |
| SCHEMBL817554 | 0.59 | ALOX5 (0.65) | PGRNOTUMMAOBTAAR1TSHR | |
| SCHEMBL31222672 | 0.59 | ALOX5 (0.65) | PGRNOTUMMAOBTAAR1TSHR | |
| SCHEMBL28874378 | 0.59 | HTT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531705-B | Bicyclic ketone sulfonamide compounds | 美国安进公司 | 2020-09-18 | — | — | CN | disclosed |