Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.64 |
| ▸ | PTK6 | Q13882 | 6/20 | 0.64 |
| ▸ | FYN | P06241 | 6/20 | 0.64 |
| ▸ | LYN | P07948 | 5/20 | 0.64 |
| ▸ | HCK | P08631 | 4/20 | 0.64 |
| ▸ | FRK | P42685 | 4/20 | 0.64 |
| ▸ | BLK | P51451 | 4/20 | 0.64 |
| ▸ | ABL1 | P00519 | 6/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 4/20 | 0.36 |
| ▸ | YES1 | P07947 | 4/20 | 0.36 |
| ▸ | FGR | P09769 | 4/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258358 | 0.78 | SRC (1.00) | SRCPTK6FYNLYNHCK | |
| SCHEMBL20132579 | 0.72 | PTK6 (0.62) | SRCPTK6FYNLYNHCK | |
| SCHEMBL31630530 | 0.64 | FYN (0.45) | SRCPTK6FYNLYNHCK | |
| SCHEMBL18250093 | 0.64 | IGF1R (0.41) | SRCPTK6FYNLYNHCK | |
| SCHEMBL18250079 | 0.64 | MTNR1A (0.47) | SRCPTK6FYNLYNHCK | |
| SCHEMBL221350 | 0.61 | NOS1 (0.67) | SRCPTK6FRKABL1KIT | |
| SCHEMBL2745009 | 0.61 | NOS3 (0.48) | SRCPTK6FRKABL1KIT | |
| SCHEMBL17003835 | 0.59 | PDE4D (0.56) | — | |
| SCHEMBL20132684 | 0.59 | SRC (0.75) | SRCPTK6FYNLYNHCK | |
| SCHEMBL18250073 | 0.58 | MTNR1A (0.41) | SRCPTK6FYNLYNHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849050-B | Compound (I) | 爱丁堡大学董事会 | 2020-10-13 | — | — | CN | disclosed |