Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Methylhydrazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylhydrazine SCHEMBL631149 | 0.94 | — | — | |
| Methylhydrazine SCHEMBL29201448 | 0.88 | — | — | |
| Methylhydrazine SCHEMBL3103 | 0.87 | — | — | |
| Methylhydrazine SCHEMBL3175579 | 0.87 | — | — | |
| Methylhydrazine SCHEMBL4168780 | 0.80 | — | — | |
| Methylhydrazine SCHEMBL1472053 | 0.80 | — | — | |
| Methylhydrazine SCHEMBL8172656 | 0.80 | — | — | |
| Methylhydrazine SCHEMBL30951729 | 0.80 | — | — | |
| Methylhydrazine SCHEMBL437692 | 0.80 | — | — | |
| Methylhydrazine SCHEMBL8766840 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117142964-A | Preparation method of 1, 3-bis (4-aminophenoxy) benzene | 天津众泰材料科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-116813487-A | Preparation method of 2, 2-bis [4- (4-aminophenoxy) phenyl ] propane | 天津众泰材料科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-111909359-B | Curing agent and preparation method and application thereof | 广东省石油与精细化工研究院 | 2022-09-13 | — | — | CN | disclosed |
| CN-111909359-A | Curing agent and preparation method and application thereof | 广东省石油与精细化工研究院 | 2020-11-10 | — | — | CN | disclosed |
| CN-104788410-B | A kind of phenyl ring aromatic rings series connection compound, its preparation method and medical usage | 中国科学院上海药物研究所 | 2017-11-17 | — | — | CN | disclosed |
| CN-103524361-B | 4, the preparation method of 4 '-diamino-2,2 '-dicarboxylate biphenyl | Tianjin Zhong Tai Chemical Industry Science Co., Ltd (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-104788410-A | Phenyl ring-aromatic ring cascaded compound, and preparation method and medical application thereof | SHANGHAI INST MATERIA MEDICA | 2015-07-22 | — | — | CN | disclosed |
| CN-103524361-A | Preparation method of 4,4'-diamido-2,2'-dicarboxylbiphenyl | CHINATECH TIANJIN CHEMICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |