SCHEMBL28476451

SCHEMBL28476451

Clc1ccccc1C1c2c(ccc3ccccc23)Oc2ccc3ccccc3c21

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 1/20 0.49
NPSR1 Q6W5P4 6/20 0.45
CFTR P13569 1/20 0.44
GOPC Q9HD26 1/20 0.44
CYP2A6 P11509 2/20 0.41
DPP4 P27487 2/20 0.41
KLK3 P07288 1/20 0.40
AR P10275 1/20 0.40
AVPR1B P47901 1/20 0.40
ACHE P22303 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416279 0.85 CYP1A2 (0.53) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL414941 0.77 CYP1A2 (0.49) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL22167524 0.77 CYP1A2 (0.49) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL28473778 0.77 NPSR1 (0.54) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL416281 0.76 CYP1A2 (0.48) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL414934 0.76 CYP1A2 (0.54) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL415460 0.76 NPSR1 (0.68) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL28470279 0.75 ALDH1A1 (0.49) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL18614964 0.74 CYP1A2 (0.49) CYP1A2CYP2C19NPSR1CFTRGOPC
SCHEMBL21662347 0.74 MEN1 (0.45) CYP1A2CYP2C19NPSR1CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111804340-B Method for preparing dibenzoxanthene derivative by catalysis of magnetic mesoporous polymeric ionic liquid 曲阜师范大学 2022-05-27 CN disclosed
CN-111804340-A Method for preparing dibenzoxanthene derivative by catalysis of magnetic mesoporous polymeric ionic liquid 曲阜师范大学 2020-10-23 CN disclosed