Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490417 | 0.86 | CYP4F2 (0.35) | ALDH1A1GAACYP4F2CYP4A11PGR | |
| SCHEMBL20302329 | 0.76 | CHRM4 (0.47) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL28494397 | 0.75 | RECQL (0.46) | ALDH1A1GAACYP4F2CYP4A11PGR | |
| SCHEMBL1620417 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL377724 | 0.71 | ACHE (0.43) | ALDH1A1GAAMAPK1HSD17B10KMT2A | |
| SCHEMBL21816687 | 0.71 | ALDH1A1 (0.47) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL3512997 | 0.69 | KDM4E (0.43) | ALDH1A1MAPK1HSD17B10MAPTKMT2A | |
| SCHEMBL4721570 | 0.67 | MAPK1 (0.45) | ALDH1A1MAPK1MAPTKMT2ALMNA | |
| SCHEMBL24892176 | 0.67 | THRB (0.36) | MAPK1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL15670001 | 0.67 | NUDT1 (0.43) | ALDH1A1PTGS1HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902404-A | Therapeutic compounds and compositions | 艾克赛特赫拉制药有限责任公司 | 2020-11-06 | — | — | CN | disclosed |