Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 16/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 16/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 14/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486272 | 0.93 | S1PR1 (0.42) | OPRM1OPRD1OPRK1S1PR1S1PR3 | |
| SCHEMBL28486275 | 0.82 | S1PR1 (0.38) | OPRM1OPRD1OPRK1S1PR1S1PR3 | |
| SCHEMBL28478495 | 0.82 | OPRM1 (0.40) | OPRM1OPRD1OPRK1S1PR1S1PR3 | |
| SCHEMBL28482119 | 0.78 | SMN1; SMN2 (0.44) | OPRM1OPRD1OPRK1CD274GRIN2D | |
| SCHEMBL11115121 | 0.76 | NFKB1 (0.55) | — | |
| SCHEMBL28481490 | 0.72 | KMT2A (0.52) | OPRM1OPRD1OPRK1CD274GRIN2D | |
| SCHEMBL3265195 | 0.72 | MEN1 (0.50) | S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL4687699 | 0.71 | KDM4E (0.54) | S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL22978445 | 0.68 | GABRP (0.40) | OPRM1OPRD1OPRK1CD274GRIN2D | |
| SCHEMBL28375723 | 0.68 | GABRP (0.40) | OPRM1OPRD1OPRK1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936466-A | Compounds for the treatment of cardiac arrhythmias and heart failure | 埃利克斯生物技术公司 | 2020-11-13 | — | — | CN | disclosed |