Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196795 | 0.89 | HTR6 (0.39) | KDM4EHTR6MEN1ALDH1A1KMT2A | |
| SCHEMBL2846314 | 0.81 | L3MBTL1 (0.33) | ROCK2 | |
| SCHEMBL1315359 | 0.80 | ROCK2 (0.35) | KDM4EMEN1ALDH1A1KMT2AROCK2 | |
| SCHEMBL21788 | 0.80 | HTR6 (0.36) | KDM4EHTR6MEN1ALDH1A1KMT2A | |
| SCHEMBL29354371 | 0.80 | HTR6 (0.36) | KDM4EHTR6MEN1ALDH1A1KMT2A | |
| SCHEMBL29353225 | 0.80 | HTR6 (0.36) | KDM4EHTR6MEN1ALDH1A1KMT2A | |
| SCHEMBL301552 | 0.79 | NPC1 (0.38) | MEN1KMT2AROCK2LMNATSHR | |
| SCHEMBL2847317 | 0.79 | KDM4E (0.33) | KDM4EMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL4988734 | 0.78 | HTR6 (0.34) | HTR6ALDH1A1LMNATSHR | |
| SCHEMBL1314189 | 0.78 | ROCK2 (0.33) | KDM4EALDH1A1ROCK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |