Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CDC25B | P30305 | 6/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CDC25C | P30307 | 1/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332817 | 0.85 | CDC25B (0.62) | METTL3TP53CDC25BCDC25ACDC25C | |
| Hydrochloric Acid SCHEMBL9332738 | 0.80 | ALDH1A1 (0.55) | METTL3TP53CDC25BCDC25ACDC25C | |
| SCHEMBL28486756 | 0.80 | FTO (0.59) | METTL3FTOMAPTLMNAKMT2A | |
| SCHEMBL30615706 | 0.80 | FTO (0.59) | METTL3FTOMAPTLMNAKMT2A | |
| SCHEMBL27937437 | 0.79 | MT-CO2 (0.68) | METTL3CDC25BCDC25ACDC25CKDM4E | |
| SCHEMBL1213901 | 0.78 | CASP1 (0.52) | TP53HSD17B10KDM4ETSHRMAPT | |
| SCHEMBL3960578 | 0.76 | BRAF (0.54) | METTL3TP53CDC25BCDC25ACDC25C | |
| SCHEMBL1203877 | 0.76 | METTL3 (0.56) | METTL3TP53CDC25BCDC25ACDC25C | |
| SCHEMBL10834558 | 0.76 | CDC25B (0.77) | METTL3TP53CDC25BCDC25ACDC25C | |
| SCHEMBL873827 | 0.75 | CASP1 (0.52) | TP53HSD17B10KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-111868037-A | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2020-10-30 | — | — | CN | disclosed |