SCHEMBL28489299

SCHEMBL28489299

Cc1ccc2c(c1)C([Hf](C)C)c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
MEN1 O00255 2/20 0.36
LMNA P02545 1/20 0.36
GPR3 P46089 2/20 0.36
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
PPIA P62937 2/20 0.33
CYP2A6 P11509 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDK2 Q15119 1/20 0.33
GAA P10253 1/20 0.32
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903253 0.90 MAOA (0.35) ELANEKMT2AALDH1A1CYP1A2HPGD
SCHEMBL6903225 0.84 GPR3 (0.46) KMT2AALDH1A1CYP1A2NPC1MEN1
SCHEMBL28502522 0.78 ACHE (0.37) ELANECYP1A2PPIACYP2A6TDP1
SCHEMBL30431051 0.75 HTR7 (0.46) ELANEKMT2AALDH1A1CYP1A2HPGD
SCHEMBL14492674 0.75 HTR7 (0.46) ELANEKMT2AALDH1A1CYP1A2HPGD
SCHEMBL16230462 0.73 HTR7 (0.47) ELANEKMT2AALDH1A1CYP1A2HPGD
SCHEMBL8749961 0.73 PGR (0.48) ELANEKMT2AALDH1A1CYP1A2HPGD
Hydrochloric Acid SCHEMBL4632310 0.73 ELANE (0.44) ELANEKMT2AALDH1A1CYP1A2HPGD
Hydrochloric Acid SCHEMBL5355296 0.72 ELANE (0.42) ELANEKMT2AALDH1A1CYP1A2HPGD
SCHEMBL27978353 0.71 GPR3 (0.34) KMT2AALDH1A1CYP1A2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN claimed
CN-112351987-B Non-coordinating anionic activators containing cations having large alkyl groups 埃克森美孚化学专利公司 2024-02-02 CN disclosed
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN disclosed
CN-114761414-A Non-coordinating anion activators containing cations with long chain alkoxy functionality 埃克森美孚化学专利公司 2022-07-15 CN disclosed
CN-112351987-A Non-coordinating anionic activators containing cations with large alkyl groups 埃克森美孚化学专利公司 2021-02-09 CN disclosed
CN-112088172-A Process for preparing non-coordinating anionic activators in aliphatic and cycloaliphatic hydrocarbon solvents 埃克森美孚化学专利公司 2020-12-15 CN disclosed
CN-112020491-A Non-coordinating anionic activators containing cations with branched alkyl groups 埃克森美孚化学专利公司 2020-12-01 CN disclosed