SCHEMBL6903253

SCHEMBL6903253

Cc1ccc2c(c1)C([Hf](C)C)c1cc(C)ccc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2A6 P11509 2/20 0.35
ELANE P08246 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
ACHE P22303 3/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
TDP1 Q9NUW8 3/20 0.31
TP53 P04637 2/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28489299 0.90 ELANE (0.41) CYP1A2CYP2A6ELANETDP1ALDH1A1
SCHEMBL28502522 0.82 ACHE (0.37) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL13825602 0.73 MAOA (0.39) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL30753570 0.72 ALDH1A1 (0.40) CYP1A2CA1CA9TDP1ALOX15
SCHEMBL23222447 0.71 DYRK1A (0.39) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL29174122 0.71 MAOB (0.38) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL15435593 0.71 TDP1 (0.39) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL5684539 0.71 TDP1 (0.40) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL8752734 0.71 DYRK1A (0.56) MAOAMAOBCYP1A2CYP2A6ELANE
SCHEMBL12378277 0.71 MAOA (0.38) MAOAMAOBCYP1A2CYP2A6ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1138796-C Bridge metallocenes for olefine copolymerization ����ɭ���ڻ�ѧר����˾ 2004-02-18 CN claimed
CN-1133660-C High temp olefin polymerization process ����ɭ���ڻ�ѧר����˾ 2004-01-07 CN claimed
CN-1328580-A Bridged metallocenes for the copolymerization of olefins EXXON MOBIL CHEM PATENTS INC (US) 2001-12-26 CN claimed
CN-1291999-A High temperature polymerization of olefins EXXON CHEMICAL PATENTS INC (US) 2001-04-18 CN claimed
CN-110845801-B Polymer composition and process for producing the same 埃克森美孚化学专利公司 2023-01-03 CN disclosed
CN-112805329-A Process for preparing a polymer composition with enhanced elasticity by employing a VTP and HMP catalyst system in a parallel process 埃克森美孚化学专利公司 2021-05-14 CN disclosed
CN-107250250-B Polymer compositions with improved rheological properties 埃克森美孚化学专利公司 2020-12-29 CN disclosed
CN-107922689-B Ethylene copolymers with in situ oil production 埃克森美孚化学专利公司 2020-09-08 CN disclosed
CN-107207807-B Process for producing polymer composition 埃克森美孚化学专利公司 2020-06-16 CN disclosed
CN-107148446-B Polymer composition and process for producing the same 埃克森美孚化学专利公司 2020-06-16 CN disclosed
CN-110845801-A Polymer composition and process for producing the same 埃克森美孚化学专利公司 2020-02-28 CN disclosed
EP-1268575-B1 NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2004-06-09 EP disclosed
US-20030083515-A1 Nitrogen-containing group-13 anionic compounds for olefin polymerization RODRIGUEZ GEORGE (US) 2003-05-01 US disclosed
EP-1268575-A2 NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-01-02 EP disclosed
WO-2001081435-A2 NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030083515-A1 Nitrogen-containing group-13 anionic compounds for olefin polymerization SFN, SLC7A5, NOTUM MAOA 2570/4885MAOB 2553/4885CYP1A2 2108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.