SCHEMBL28494149

SCHEMBL28494149

C[Si](C)(C)OS(=O)(=O)c1ccc(S(=O)(=O)O[Si](C)(C)C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.36
GAA P10253 2/20 0.35
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
VDR P11473 1/20 0.33
HTT P42858 4/20 0.32
LMNA P02545 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12212901 0.93 CA2 (0.41) HTTLMNASMN1; SMN2ALDH1A1TSHR
SCHEMBL2187749 0.91 GAA (0.50) PKMGAAKEAP1NFE2L2VDR
SCHEMBL28738302 0.89 NR1H2 (0.31) PKMKEAP1NFE2L2
SCHEMBL28494151 0.89 LMNA (0.46) HTTLMNASMN1; SMN2TDP1L3MBTL1
SCHEMBL10711576 0.89 CA2 (0.45) GAALMNATDP1ALDH1A1CA1
SCHEMBL8633771 0.89 MEN1 (0.43) POLBALDH1A1TSHRCA1CA2
SCHEMBL10799130 0.89 ALDH1A1 (0.48) GAATDP1ALDH1A1MAPK1CA1
SCHEMBL10793501 0.89 ENPP2 (0.50) PKMGAALMNASMN1; SMN2POLB
SCHEMBL1059042 0.88 ALDH1A1 (0.46) PKMHTTLMNASMN1; SMN2TDP1
SCHEMBL10798428 0.87 PKM (0.57) PKMGAAHTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143028-B Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2021-07-27 CN disclosed
CN-112143028-A Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2020-12-29 CN disclosed