Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494149 | 0.89 | PKM (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL12212901 | 0.83 | CA2 (0.41) | MEN1KMT2ACA1CA2RAB9A | |
| SCHEMBL2187749 | 0.81 | GAA (0.50) | MEN1KMT2ACA1CA2MMP1 | |
| SCHEMBL28494151 | 0.79 | LMNA (0.46) | POLBALDH1A1TSHR | |
| SCHEMBL10793501 | 0.79 | ENPP2 (0.50) | MEN1KMT2ACA1CA2EDNRA | |
| SCHEMBL10711576 | 0.79 | CA2 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10799130 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ACA1CA2MMP1 | |
| SCHEMBL28738302 | 0.79 | NR1H2 (0.31) | — | |
| SCHEMBL4098354 | 0.79 | KMT2A (0.40) | MEN1KMT2ASOS1CA1CA2 | |
| SCHEMBL1059042 | 0.78 | ALDH1A1 (0.46) | KMT2ACA1CA2RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705702-A | REACTING AN ARYL GRIGNARD REAGENT WITH THIONYL CHLORIDE, THEN WITH TRIORGANOSILYL SULFONATE OR TRIORGANOSILYLHALIDE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |