Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.45 |
| ▸ | MMP9 | P14780 | 7/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212094 | 0.86 | LMNA (0.48) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL1683293 | 0.79 | LMNA (0.58) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL472546 | 0.77 | LMNA (0.44) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL11273946 | 0.76 | MMP13 (0.43) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL5272059 | 0.76 | LMNA (0.43) | MMP2MMP9MMP3LMNAMMP13 | |
| Butethal SCHEMBL44262 | 0.76 | LMNA (0.67) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL11256550 | 0.76 | MMP13 (0.43) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL8348835 | 0.75 | LMNA (0.59) | MMP2MMP9MMP3LMNAMMP13 | |
| SCHEMBL5033111 | 0.74 | LMNA (0.41) | MMP2MMP9MMP3LMNAKDM4E | |
| SCHEMBL6691265 | 0.74 | SMN1; SMN2 (0.46) | MMP2MMP9MMP3HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129777-A1 | KIT FOR FIXING A DENTAL RESTORATION MATERIAL ON A TOOTH SUBSTANCE | ERNST MÜHLBAUER GMBH & CO. KG (DE) | 2010-05-27 | — | — | US | disclosed |