SCHEMBL28501773

SCHEMBL28501773

CC[Si](CC)(CC)OS(=O)(=O)c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
NT5E P21589 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
CYP2D6 P10635 3/20 0.38
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 3/20 0.35
POLB P06746 1/20 0.35
HTT P42858 2/20 0.35
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
S1PR3 Q99500 1/20 0.33
ADORA2A P29274 2/20 0.33
ADORA2B P29275 2/20 0.33
CYP1A2 P05177 2/20 0.33
NAPRT Q6XQN6 1/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28501772 0.90 CA2 (0.35) LMNAALDH1A1TSHRSMN1; SMN2TDP1
SCHEMBL3938648 0.83 GAA (0.45) ALDH1A1SMN1; SMN2KMT2ACYP2C9
SCHEMBL28501797 0.83 ALDH1A1 (0.43) ALDH1A1TSHRSMN1; SMN2TDP1S1PR3
SCHEMBL3939217 0.81 ALDH1A1 (0.43) ALDH1A1TDP1KDM4EPOLBMAPT
SCHEMBL4098354 0.81 KMT2A (0.40) ALDH1A1TSHRHTTL3MBTL1HSD17B10
SCHEMBL2057739 0.81 CA2 (0.50) LMNAALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL2057944 0.81 PSIP1 (0.48) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E
SCHEMBL3939064 0.80 PKM (0.52) LMNAALDH1A1SMN1; SMN2TDP1HTT
SCHEMBL8661128 0.79 ALDH1A1 (0.47) LMNAALDH1A1TSHRSMN1; SMN2CYP2D6
SCHEMBL3938489 0.79 KIF11 (0.43) LMNAALDH1A1SMN1; SMN2KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143028-B Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2021-07-27 CN disclosed
CN-112143028-A Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2020-12-29 CN disclosed