SCHEMBL28501772

SCHEMBL28501772

CC[Si](CC)(CC)OS(=O)(=O)c1ccc(S(=O)(=O)O[Si](CC)(CC)CC)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.35
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35
CA7 P43166 3/20 0.35
CA9 Q16790 3/20 0.35
GAA P10253 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.34
F2 P00734 1/20 0.34
MAPT P10636 1/20 0.34
VDR P11473 1/20 0.34
PSIP1 O75475 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3938648 0.92 GAA (0.45) CA2CA12CA1CA7CA9
SCHEMBL4098354 0.90 KMT2A (0.40) CA2CA1HTTALDH1A1MAPK1
SCHEMBL2057739 0.90 CA2 (0.50) CA2SMN1; SMN2LMNAHTTALDH1A1
SCHEMBL3939217 0.90 ALDH1A1 (0.43) CA2CA12CA1CA7CA9
SCHEMBL28501773 0.90 LMNA (0.42) SMN1; SMN2LMNAHTTALDH1A1MAPK1
SCHEMBL2057944 0.90 PSIP1 (0.48) CA2CA12CA1CA7CA9
SCHEMBL3939064 0.89 PKM (0.52) CA2CA1GAASMN1; SMN2LMNA
SCHEMBL8661128 0.87 ALDH1A1 (0.47) CA2CA1CA9GAASMN1; SMN2
SCHEMBL3938489 0.87 KIF11 (0.43) CA2CA1CA9GAASMN1; SMN2
SCHEMBL3939932 0.86 CA1 (0.46) CA2CA12CA1CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143028-B Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2021-07-27 CN disclosed
CN-112143028-A Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2020-12-29 CN disclosed