Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.69 |
| ▸ | FAAH | O00519 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698063 | 1.00 | MGLL (0.69) | MGLLFAAHKMT2AAPAF1ALDH1A1 | |
| SCHEMBL146412 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1TP53MAPT | |
| SCHEMBL7218376 | 0.79 | MGLL (0.82) | MGLLFAAHKMT2AAPAF1TP53 | |
| SCHEMBL5766969 | 0.79 | KMT2A (0.73) | KMT2AAPAF1ALDH1A1TP53CYP1A2 | |
| SCHEMBL8950019 | 0.77 | MGLL (0.86) | MGLLFAAHALDH1A1TP53MAPT | |
| SCHEMBL21215698 | 0.77 | MGLL (0.86) | MGLLFAAHALDH1A1TP53MAPT | |
| SCHEMBL18668985 | 0.77 | ALDH1A1 (0.70) | KMT2AAPAF1ALDH1A1TP53CYP1A2 | |
| SCHEMBL140975 | 0.75 | MGLL (0.72) | MGLLFAAHKMT2AALDH1A1MAPT | |
| SCHEMBL10341809 | 0.75 | KMT2A (0.62) | KMT2AAPAF1ALDH1A1TP53CYP1A2 | |
| SCHEMBL30081910 | 0.74 | ALDH1A1 (1.00) | APAF1ALDH1A1TP53CYP1A2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028808-B | Preparation method of N-substituted-3-methyl mercapto-4-morpholinyl maleimide compound | 温州医科大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-112028808-A | Preparation method of N-substituted-3-methylmercapto-4-morpholinyl maleimide compound | 温州医科大学 | 2020-12-04 | — | — | CN | disclosed |