Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858681 | 0.96 | KDM4E (0.43) | KDM4ELMNAMAPTCYP2C19HSD17B10 | |
| Carbon Monoxide SCHEMBL10727342 | 0.91 | KDM4E (0.40) | KDM4ELMNAMAPTCYP2C19HSD17B10 | |
| Formaldehyde SCHEMBL11362689 | 0.91 | KDM4E (0.40) | KDM4ELMNAMAPTCYP2C19HSD17B10 | |
| Cyclohexane SCHEMBL28510424 | 0.91 | KDM4E (0.40) | KDM4ELMNAMAPTCYP2C19HSD17B10 | |
| Carbon Monoxide SCHEMBL11362686 | 0.89 | KDM4E (0.39) | KDM4ELMNAMAPTCYP2C19HSD17B10 | |
| SCHEMBL10728992 | 0.80 | ALDH1A1 (0.50) | KDM4ELMNAMAPTHSD17B10TDP1 | |
| SCHEMBL1095111 | 0.79 | KEAP1 (0.46) | LMNAMAPTCYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL9517922 | 0.78 | KEAP1 (0.45) | LMNAMAPTCYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL17570461 | 0.77 | HSD11B1 (0.42) | MAPTTSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10044347 | 0.76 | NPC1 (0.35) | KDM4ELMNAMAPTHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112250633-B | 1,2-di (diphenylphosphine alkyl amido) -1,2-disubstituted ethane and synthesis and application thereof | 浙江大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-112250633-A | 1, 2-di (diphenylphosphine alkyl amido) -1, 2-disubstituted ethane and synthesis and application thereof | 浙江大学 | 2021-01-22 | — | — | CN | disclosed |