Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28120658 | 0.81 | KMT2A (0.41) | KDM4EKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL6123415 | 0.79 | KDM4E (0.41) | KDM4EKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL1333179 | 0.78 | HTT (0.54) | KDM4EKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL10842060 | 0.74 | KMT2A (0.67) | KDM4EKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL27617492 | 0.74 | PKM (0.48) | KDM4EKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL28889406 | 0.70 | KDM4E (0.38) | KDM4EKMT2AMEN1POLBGAA | |
| SCHEMBL28512724 | 0.70 | IDO1 (0.60) | KDM4EKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL21246906 | 0.70 | L3MBTL1 (0.59) | KDM4EKMT2AMEN1 | |
| SCHEMBL28824689 | 0.70 | KMT2A (0.50) | KDM4EKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL28852179 | 0.69 | IDO1 (0.40) | KDM4EKMT2AMEN1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112294798-A | Composition for reducing absorption of lipase inhibitor in digestive tract | 中山万汉制药有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-112263575-A | Composition containing orlistat and indoxyl acetamide compound and application thereof | 中山万汉制药有限公司 | 2021-01-26 | — | — | CN | claimed |
| CN-112294798-A | Composition for reducing absorption of lipase inhibitor in digestive tract | 中山万汉制药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112294798-A | Composition for reducing absorption of lipase inhibitor in digestive tract | 中山万汉制药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112263575-A | Composition containing orlistat and indoxyl acetamide compound and application thereof | 中山万汉制药有限公司 | 2021-01-26 | — | — | CN | disclosed |