SCHEMBL28519966

SCHEMBL28519966

C=C(C)C(=O)C(CCCCC(N)CCC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
S1PR2 O95136 5/20 0.37
S1PR1 P21453 5/20 0.37
S1PR3 Q99500 5/20 0.37
S1PR4 O95977 4/20 0.37
GRIK1 P39086 3/20 0.37
GRIK2 Q13002 3/20 0.37
SLC1A2 P43004 3/20 0.37
SLC1A1 P43005 3/20 0.37
SLC1A3 P43003 2/20 0.36
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688047 0.97 ALDH1A1 (0.49) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL28453064 0.93 ALDH1A1 (0.45) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL28666825 0.90 ALDH1A1 (0.43) ALDH1A1GRIK1GRIK2SLC1A2SLC1A1
SCHEMBL28675100 0.87 ALDH1A1 (0.41) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL9132316 0.82 GPR84 (0.52) GRIK1GRIK2GPR84FFAR1MAPT
SCHEMBL5830000 0.82 CA2 (0.47) SLC1A2SLC1A1SLC1A3CHRM1AKR1A1
SCHEMBL15463418 0.81 GRIK1 (0.47) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL5678264 0.79 GSR (0.48) ALDH1A1SLC6A3
SCHEMBL17335976 0.77 CPB2 (0.47) ALDH1A1SLC6A3
SCHEMBL17335986 0.77 CPB2 (0.47) ALDH1A1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106573015-B Enteric elastomer 麻省理工学院 2021-11-26 CN disclosed
CN-106714893-B Self-assembled residence device and related method 麻省理工学院 2021-01-01 CN disclosed