SCHEMBL5830000

SCHEMBL5830000

C=C(C)C(=O)C(CCCC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.47
MAPK1 P28482 1/20 0.47
GPR84 Q9NQS5 3/20 0.41
FFAR1 O14842 1/20 0.41
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
MAPT P10636 1/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
CHRM1 P11229 1/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132316 0.92 GPR84 (0.52) CA2GPR84FFAR1MAPTLCK
SCHEMBL28453064 0.89 ALDH1A1 (0.45) CA2MAPK1GPR84FFAR1SLC1A3
SCHEMBL11127010 0.83 CA2 (0.50) CA2MAPK1GPR84FFAR1SLC1A3
SCHEMBL28688047 0.82 ALDH1A1 (0.49) CA2MAPK1GPR84FFAR1SLC1A3
SCHEMBL28519966 0.82 ALDH1A1 (0.53) GPR84FFAR1SLC1A3SLC1A2SLC1A1
Methacrylic Acid SCHEMBL27609901 0.82 CA2 (0.45) CA2MAPK1GPR84FFAR1SLC1A3
SCHEMBL17336351 0.82 CPB2 (0.42) HDAC1HDAC2TDP1TSHR
SCHEMBL7823790 0.80 CA2 (0.52) CA2MAPK1GPR84FFAR1SLC1A3
SCHEMBL5678264 0.80 GSR (0.48) SLC6A3
SCHEMBL39429 0.79 CA2 (0.61) CA2MAPK1GPR84FFAR1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7071240-B1 Carboxylic cationites and methods of manufacture POLYGRAN LTD. (IL) 2006-07-04 US claimed
EP-1084150-A4 CARBOXYLIC CATIONITES AND METHODS OF MANUFACTURE POLYGRAN LTD (IL) 2002-05-22 EP claimed
EP-1084150-A1 CARBOXYLIC CATIONITES AND METHODS OF MANUFACTURE Polygran Ltd. (IL) 2001-03-21 EP claimed
WO-1999058577-A1 CARBOXYLIC CATIONITES AND METHODS OF MANUFACTURE POLYGRAN LTD. (IL) 1999-11-18 WO claimed
CN-100564432-C The manufacture method of foams OJI PAPER CO (JP) 2009-12-02 CN disclosed
CN-100545198-C Sheet-like foam and process for producing the same OJI PAPER CO (JP) 2009-09-30 CN disclosed
CN-101031610-A Process for producing foam OJI PAPER CO (JP) 2007-09-05 CN disclosed
CN-1823120-A Foamed product in a sheet form and method for production thereof OJI PAPER CO (JP) 2006-08-23 CN disclosed
US-7071240-B1 Carboxylic cationites and methods of manufacture POLYGRAN LTD. (IL) 2006-07-04 US disclosed
EP-1084150-A4 CARBOXYLIC CATIONITES AND METHODS OF MANUFACTURE POLYGRAN LTD (IL) 2002-05-22 EP disclosed
EP-1084150-A1 CARBOXYLIC CATIONITES AND METHODS OF MANUFACTURE Polygran Ltd. (IL) 2001-03-21 EP disclosed
US-6018033-A BIODEGRADABLE; FOR CONTROLLED RELEASE OF DRUGS PURDUE RESEARCH FOUNDATION (US) 2000-01-25 US disclosed
WO-1999058577-A1 CARBOXYLIC CATIONITES AND METHODS OF MANUFACTURE POLYGRAN LTD. (IL) 1999-11-18 WO disclosed
WO-1998051694-A2 HYDROPHILIC, HYDROPHOBIC, AND THERMOREVERSIBLE SACCHARIDE GELS AND FOAMS, AND METHODS FOR PRODUCING SAME PURDUE RESEARCH FOUNDATION (US) 1998-11-19 WO disclosed