SCHEMBL5678264

SCHEMBL5678264

C=C(C)C(=O)C(CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.48
RNPEP Q9H4A4 1/20 0.47
CPB2 Q96IY4 6/20 0.45
PAOX Q6QHF9 3/20 0.38
GABRR1 P24046 2/20 0.38
FOLH1 Q04609 1/20 0.38
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLG P00747 1/20 0.34
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
RECQL P46063 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17335968 0.98 CPB2 (0.47) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL17335987 0.98 CPB2 (0.47) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL17335976 0.98 CPB2 (0.47) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL17335986 0.98 CPB2 (0.47) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL8713920 0.98 CPB2 (0.47) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL17335993 0.98 CPB2 (0.47) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL17336351 0.94 CPB2 (0.42) GSRRNPEPCPB2PAOXGABRR1
SCHEMBL15463361 0.86 GABRR1 (0.46) GSRRNPEPCPB2GABRR1
SCHEMBL9132316 0.81 GPR84 (0.52)
SCHEMBL5830000 0.80 CA2 (0.47) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106573015-B Enteric elastomer 麻省理工学院 2021-11-26 CN claimed
US-11083690-B2 Enteric elastomers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-08-10 US claimed
US-20200030234-A1 ENTERIC ELASTOMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-01-30 US claimed
US-20170128576-A1 ENTERIC ELASTOMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-05-11 US claimed
US-20170106099-A1 RESIDENCE STRUCTURES AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-04-20 US claimed
EP-3154553-A1 ENTERIC ELASTOMERS Massachusetts Institute Of Technology (US) 2017-04-19 EP claimed
EP-3155024-A1 RESIDENCE STRUCTURES AND RELATED METHODS Massachusetts Institute Of Technology (US) 2017-04-19 EP claimed
CN-106573015-A enteric elastomer 麻省理工学院 2017-04-19 CN claimed
CN-106573999-A Residence structures and related methods 麻省理工学院 2017-04-19 CN claimed
WO-2015191920-A1 RESIDENCE STRUCTURES AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-12-17 WO claimed
WO-2015191922-A1 ENTERIC ELASTOMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-12-17 WO claimed
US-20050165136-A1 Glass-ionomer cements containing amino acids UAB RESEARCH FOUNDATION (US) 2005-07-28 US claimed
US-5415864-A Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1995-05-16 US claimed
EP-0544671-A4 COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING PH-DEPENDENT SWELLING 1993-09-15 EP claimed
EP-0544671-A1 COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1993-06-09 EP claimed
WO-1991016057-A1 COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING UNIVERSITY OF UTAH (US) 1991-10-31 WO claimed
EP-3155024-B2 RESIDENCE STRUCTURES AND RELATED METHODS MASSACHUSETTS INST TECHNOLOGY (US) 2025-06-18 EP disclosed
EP-4516322-A2 RESIDENCE STRUCTURES AND RELATED METHODS Massachusetts Institute of Technology (US) 2025-03-05 EP disclosed
WO-1998051694-A2 HYDROPHILIC, HYDROPHOBIC, AND THERMOREVERSIBLE SACCHARIDE GELS AND FOAMS, AND METHODS FOR PRODUCING SAME PURDUE RESEARCH FOUNDATION (US) 1998-11-19 WO disclosed
US-5415864-A Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1995-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170106099-A1 RESIDENCE STRUCTURES AND RELATED METHODS SI, VIP, GIPR GSR 567/4885RNPEP 2572/4885CPB2 2338/4885
US-20200030234-A1 ENTERIC ELASTOMERS SI, GNE, MLN GSR 2413/4885RNPEP 3857/4885CPB2 1885/4885
US-20170128576-A1 ENTERIC ELASTOMERS SI, GNE, MLN GSR 2413/4885RNPEP 3857/4885CPB2 1885/4885
US-11083690-B2 Enteric elastomers SI, GNE, MLN GSR 2413/4885RNPEP 3857/4885CPB2 1885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.