Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854509 | 0.85 | KDM4E (0.50) | TAAR1GLANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2859076 | 0.84 | KEAP1 (0.42) | ALDH1A1 | |
| SCHEMBL2855547 | 0.84 | TAAR1 (0.54) | TAAR1GLANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2852810 | 0.84 | KDM4E (0.48) | GLANPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL2859861 | 0.82 | TAAR1 (0.51) | TAAR1GLASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2857181 | 0.82 | CCR1 (0.47) | GAA | |
| SCHEMBL2860253 | 0.81 | PLAAT3 (0.47) | TAAR1GLANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2854346 | 0.81 | MAPT (0.52) | TAAR1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL2859594 | 0.81 | TAAR1 (0.45) | TAAR1SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL2851930 | 0.81 | TAAR1 (0.47) | TAAR1GLANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |