Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853334 | 0.92 | CCR1 (0.47) | P2RX7CCR1NPSR1MAPK1MAPT | |
| SCHEMBL2853388 | 0.91 | CCR1 (0.48) | P2RX7CCR1POLBRAB9AMAPT | |
| SCHEMBL2859091 | 0.91 | CCR1 (0.46) | P2RX7CCR1SMOMAPK1RAB9A | |
| SCHEMBL2856356 | 0.91 | ALDH1A1 (0.47) | CCR1NPSR1POLBRAB9AMAPT | |
| SCHEMBL2850857 | 0.90 | TP53 (0.46) | P2RX7NPSR1PTPN1MAPTTP53 | |
| SCHEMBL2860458 | 0.90 | TP53 (0.46) | P2RX7NPSR1PTPN1MAPTTP53 | |
| SCHEMBL2854322 | 0.90 | ABCB1 (0.45) | P2RX7CCR1MAPK1MAPT | |
| SCHEMBL2855710 | 0.90 | LMNA (0.46) | P2RX7CCR1SMOMAPK1POLB | |
| SCHEMBL2854804 | 0.90 | MAPK1 (0.48) | P2RX7CCR1SMOMAPK1POLB | |
| SCHEMBL2854847 | 0.90 | ALDH1A1 (0.48) | P2RX7CCR1SMOMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |