Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407534 | 1.00 | PDK2 (0.38) | PDK2ACHEELANEALDH1A1SMN1; SMN2 | |
| SCHEMBL28529344 | 0.82 | HTR2A (0.49) | ACHEHTR2ANOS3NOS2HTR1A | |
| SCHEMBL29407071 | 0.82 | HTR2A (0.49) | ACHEHTR2ANOS3NOS2HTR1A | |
| SCHEMBL28528151 | 0.81 | DRD1 (0.46) | PDK2ACHEALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL29407087 | 0.81 | DRD1 (0.46) | PDK2ACHEALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL11141197 | 0.70 | PNMT (0.42) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL11523523 | 0.68 | ACHE (0.53) | ACHESMN1; SMN2 | |
| SCHEMBL5952175 | 0.67 | ENPP1 (0.36) | ACHEALDH1A1SMN1; SMN2HTR1ADRD2 | |
| SCHEMBL8749800 | 0.66 | PGR (0.48) | PDK2ELANEALDH1A1SMN1; SMN2PPIA | |
| SCHEMBL547186 | 0.65 | ALDH1A1 (0.53) | ACHEELANEALDH1A1SMN1; SMN2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441875-B | Method for copper photocatalytic synthesis of 9-trifluoromethyl-9, 10-dihydrophenanthrene compound | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112441874-B | Method for synthesizing 9-trifluoromethyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112441874-A | Method for synthesizing 9-trifluoromethyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis | 浙江工业大学 | 2021-03-05 | — | — | CN | disclosed |
| CN-112441875-A | Method for copper photocatalytic synthesis of 9-trifluoromethyl-9, 10-dihydrophenanthrene compound | 浙江工业大学 | 2021-03-05 | — | — | CN | disclosed |