Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407087 | 1.00 | DRD1 (0.46) | DRD1DRD2DRD4DRD5DRD3 | |
| SCHEMBL29407534 | 0.81 | PDK2 (0.38) | DRD2PDK2ACHEALDH1A1HTR2A | |
| SCHEMBL28523441 | 0.81 | PDK2 (0.38) | DRD2PDK2ACHEALDH1A1HTR2A | |
| SCHEMBL29407071 | 0.78 | HTR2A (0.49) | DRD2ACHEHTR2ATSHR | |
| SCHEMBL28529344 | 0.78 | HTR2A (0.49) | DRD2ACHEHTR2ATSHR | |
| SCHEMBL5953390 | 0.69 | HDAC4 (0.43) | DRD2MAPTNPC1HPGDRAB9A | |
| SCHEMBL7135478 | 0.69 | CYP19A1 (0.49) | DRD1DRD2DRD3LMNAMAPT | |
| SCHEMBL3287680 | 0.69 | ALDH1A1 (0.56) | DRD1DRD2DRD4DRD5DRD3 | |
| SCHEMBL11686997 | 0.66 | MTNR1A (0.54) | DRD1DRD2DRD4DRD5DRD3 | |
| SCHEMBL6603160 | 0.66 | LMNA (0.44) | DRD2DRD3LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441875-B | Method for copper photocatalytic synthesis of 9-trifluoromethyl-9, 10-dihydrophenanthrene compound | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112441874-B | Method for synthesizing 9-trifluoromethyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112441874-A | Method for synthesizing 9-trifluoromethyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis | 浙江工业大学 | 2021-03-05 | — | — | CN | disclosed |
| CN-112441875-A | Method for copper photocatalytic synthesis of 9-trifluoromethyl-9, 10-dihydrophenanthrene compound | 浙江工业大学 | 2021-03-05 | — | — | CN | disclosed |