Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853258 | 0.91 | NPY5R (0.45) | ALDH1A1FAAHCYP3A4MAPK1NPY5R | |
| SCHEMBL2854269 | 0.91 | RAB9A (0.46) | ALDH1A1RAB9ANPC1BRAFCCR1 | |
| SCHEMBL2856385 | 0.87 | CCR1 (0.44) | RXFP1RAB9ABRAFCCR1LMNA | |
| SCHEMBL2861572 | 0.85 | CA1 (0.49) | — | |
| SCHEMBL2854572 | 0.84 | RAB9A (0.44) | CYP3A4KDM4ERAB9ANPC1BRAF | |
| SCHEMBL2852361 | 0.84 | KDM4E (0.47) | ALDH1A1MAPK1NPY5RKDM4EHPGD | |
| SCHEMBL2850550 | 0.83 | CCR1 (0.54) | KDM4ECCR1P2RX7 | |
| SCHEMBL2850032 | 0.82 | NPC1 (0.56) | ALDH1A1RXFP1NPY5RKDM4ERAB9A | |
| SCHEMBL2861646 | 0.82 | NPC1 (0.42) | NPY5RKDM4ERAB9ANPC1BRAF | |
| SCHEMBL2850258 | 0.82 | MAPT (0.51) | CYP3A4NPY5RKDM4EHPGDBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |