Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DDT | P30046 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854814 | 0.92 | TP53 (0.47) | CCR1KDM4EDDT | |
| SCHEMBL2854543 | 0.92 | CCR1 (0.54) | CCR1P2RX7NPSR1DDT | |
| SCHEMBL2853351 | 0.90 | CCR1 (0.62) | CCR1P2RX7KDM4ENPSR1 | |
| SCHEMBL2853277 | 0.89 | CCR1 (0.50) | CCR1P2RX7SMO | |
| SCHEMBL2857457 | 0.89 | CCR1 (0.49) | CCR1P2RX7SMOKDM4ENPSR1 | |
| SCHEMBL2855710 | 0.88 | LMNA (0.46) | CCR1P2RX7SMO | |
| SCHEMBL2854804 | 0.88 | MAPK1 (0.48) | CCR1P2RX7SMOKDM4E | |
| SCHEMBL2863210 | 0.84 | CCR1 (0.50) | CCR1P2RX7SMOKDM4ENPSR1 | |
| SCHEMBL2854847 | 0.84 | ALDH1A1 (0.48) | CCR1P2RX7SMOKDM4E | |
| SCHEMBL2856797 | 0.84 | P2RX7 (0.45) | CCR1P2RX7SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |