Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858157 | 0.94 | POLB (0.55) | POLBP2RX7GAATDP1HPGD | |
| SCHEMBL2857338 | 0.91 | RAB9A (0.47) | POLBP2RX7GAATDP1HPGD | |
| SCHEMBL2850369 | 0.90 | P2RX7 (0.56) | POLBP2RX7CCR1TP53NR3C1 | |
| SCHEMBL2858580 | 0.90 | HIF1A (0.43) | POLBP2RX7CCR1NPC1RAB9A | |
| SCHEMBL2853344 | 0.87 | HPGD (0.55) | P2RX7HPGDLMNACCR1NPC1 | |
| SCHEMBL2863134 | 0.85 | CCR1 (0.48) | P2RX7HPGDCCR1ALDH1A1 | |
| SCHEMBL2857989 | 0.85 | P2RX7 (0.49) | POLBP2RX7GAATDP1HPGD | |
| SCHEMBL2853267 | 0.85 | HPGD (0.55) | P2RX7HPGDLMNACCR1NPC1 | |
| SCHEMBL2851589 | 0.82 | MTNR1A (0.48) | HPGDTP53ALDH1A1 | |
| SCHEMBL2852886 | 0.81 | CCR1 (0.62) | POLBP2RX7GAATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |