Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856797 | 0.92 | P2RX7 (0.45) | CCR1P2RX7SMO | |
| SCHEMBL2852556 | 0.91 | TDP1 (0.44) | CCR1MEN1POLBKMT2ATP53 | |
| SCHEMBL2850550 | 0.89 | CCR1 (0.54) | CCR1P2RX7SMO | |
| SCHEMBL2860466 | 0.89 | RCE1 (0.47) | CCR1MEN1POLBKMT2AP2RX7 | |
| SCHEMBL2853351 | 0.88 | CCR1 (0.62) | CCR1P2RX7 | |
| SCHEMBL2854330 | 0.87 | CCR1 (0.52) | CCR1POLB | |
| SCHEMBL2857457 | 0.87 | CCR1 (0.49) | CCR1P2RX7SMO | |
| SCHEMBL2854804 | 0.86 | MAPK1 (0.48) | CCR1POLBSMN1; SMN2P2RX7TP53 | |
| SCHEMBL2855708 | 0.86 | P2RX7 (0.44) | CCR1POLBSMN1; SMN2P2RX7LMNA | |
| SCHEMBL2852520 | 0.86 | TP53 (0.47) | MEN1POLBKMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |