Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858522 | 0.92 | CCR1 (0.43) | P2RX7CCR1ALDH1A1KDM4ELMNA | |
| SCHEMBL2852117 | 0.89 | P2RX7 (0.48) | P2RX7CCR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2856615 | 0.89 | P2RX7 (0.48) | P2RX7CCR1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2853277 | 0.86 | CCR1 (0.50) | P2RX7CCR1LMNASMN1; SMN2SMO | |
| SCHEMBL2860466 | 0.85 | RCE1 (0.47) | P2RX7CCR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2852975 | 0.85 | CCR1 (0.55) | CCR1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL2854804 | 0.85 | MAPK1 (0.48) | P2RX7CCR1ALDH1A1KDM4EMAPT | |
| SCHEMBL2856797 | 0.84 | P2RX7 (0.45) | P2RX7CCR1ALDH1A1L3MBTL1NR3C1 | |
| SCHEMBL2853809 | 0.84 | P2RX7 (0.49) | P2RX7ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL2850550 | 0.83 | CCR1 (0.54) | P2RX7CCR1KDM4ENPSR1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |