Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524820 | 0.90 | ALDH1A1 (0.44) | HSD17B10MMP13MMP9MMP1ADAM17 | |
| SCHEMBL28525183 | 0.87 | ALDH1A1 (0.44) | HSD17B10MAPTALDH1A1HTTTSHR | |
| SCHEMBL28533016 | 0.74 | EGLN1 (0.41) | HSD17B10MMP13MMP9MMP1ADAM17 | |
| SCHEMBL28524818 | 0.72 | ALDH1A1 (0.42) | HSD17B10MAPTALDH1A1HTTTSHR | |
| SCHEMBL28522379 | 0.71 | PDE4A (0.53) | HSD17B10MAPTALDH1A1HTTTSHR | |
| SCHEMBL28525182 | 0.70 | SMN1; SMN2 (0.52) | HSD17B10MAPTALDH1A1HTTTSHR | |
| SCHEMBL28523856 | 0.64 | HCAR3 (0.34) | HSD17B10MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1465523 | 0.63 | ALDH1A1 (0.87) | HSD17B10ALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL9149721 | 0.62 | ALDH1A1 (0.84) | HSD17B10ALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL29183282 | 0.62 | ALDH1A1 (0.84) | HSD17B10ALDH1A1HTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279044-B | Pyrimidine hydroxamic acid derivative and preparation method and application thereof | 厦门市博瑞来医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |