SCHEMBL28534273

SCHEMBL28534273

CC1(Cc2ccccc2)[C@@H](O)CC[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
MAOA P21397 6/20 0.41
MAOB P27338 6/20 0.41
SLC18A3 Q16572 2/20 0.38
LMNA P02545 1/20 0.38
KDM1A O60341 3/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541573 1.00 ALDH1A1 (0.41) ALDH1A1MAOAMAOBSLC18A3LMNA
SCHEMBL28527487 0.81 TRPA1 (0.39) LMNAKDM1AMAPK1
SCHEMBL28537781 0.79 HSD11B1 (0.44)
SCHEMBL28546864 0.74 MEN1 (0.44) ALDH1A1MAPK1
SCHEMBL1642227 0.69 ALDH1A1 (0.39) ALDH1A1
SCHEMBL28341919 0.68 FUCA1 (0.44) ALDH1A1LMNA
SCHEMBL16822114 0.68 LMNA (0.52) SLC18A3LMNA
SCHEMBL24587063 0.67 MAOA (0.37) ALDH1A1MAOAMAOBKDM1A
SCHEMBL1644281 0.67 GRIN2B (0.49)
SCHEMBL26934642 0.67 MAOA (0.37) ALDH1A1MAOAMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112522329-B Preparation method of optically pure 2, 2-disubstituted-1, 3-cyclopentanediol 中国科学院天津工业生物技术研究所 2021-10-08 CN disclosed
CN-112522329-A Preparation method of optically pure 2, 2-disubstituted-1, 3-cyclopentanediol 中国科学院天津工业生物技术研究所 2021-03-19 CN disclosed