Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527487 | 0.80 | TRPA1 (0.39) | SSTR1SSTR4SLC6A4SLC6A3 | |
| SCHEMBL28534273 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL28541573 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL25209309 | 0.70 | PNMT (0.48) | HSD11B1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30174702 | 0.70 | PNMT (0.48) | HSD11B1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28546864 | 0.70 | MEN1 (0.44) | HSD11B1PNMTTAAR1 | |
| SCHEMBL31374947 | 0.68 | SLC6A4 (0.46) | HSD11B1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25518220 | 0.68 | PNMT (0.46) | HSD11B1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13504118 | 0.68 | TAAR1 (0.44) | HSD11B1PNMTSTSSSTR1SSTR4 | |
| SCHEMBL13343939 | 0.68 | ACAT2 (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112522329-B | Preparation method of optically pure 2, 2-disubstituted-1, 3-cyclopentanediol | 中国科学院天津工业生物技术研究所 | 2021-10-08 | — | — | CN | disclosed |
| CN-112522329-A | Preparation method of optically pure 2, 2-disubstituted-1, 3-cyclopentanediol | 中国科学院天津工业生物技术研究所 | 2021-03-19 | — | — | CN | disclosed |