Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426023 | 0.87 | GAA (0.48) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL2374142 | 0.79 | MEN1 (0.80) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30556513 | 0.78 | RXFP1 (0.53) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL7484346 | 0.77 | GAA (0.48) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL5157924 | 0.76 | GAA (0.50) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL12099189 | 0.76 | MRGPRX1 (0.57) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL11306685 | 0.75 | LMNA (0.63) | ALDH1A1KMT2AMAPTGAAMEN1 | |
| SCHEMBL7328152 | 0.75 | GABRP (0.57) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL5161867 | 0.75 | GAA (0.48) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL10813064 | 0.74 | GABRP (0.76) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586447-B | Benzodiazepine compound and preparation method and application thereof | 中国人民解放军第四军医大学 | 2021-01-29 | — | — | CN | disclosed |