Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15320658 | 0.87 | VCAM1 (0.51) | VCAM1PTGESARALDH1A1LMNA | |
| SCHEMBL3522985 | 0.83 | VCAM1 (0.54) | VCAM1ARALDH1A1LMNA | |
| SCHEMBL23832425 | 0.80 | AR (0.51) | PTGESAR | |
| SCHEMBL30104270 | 0.80 | AR (0.51) | PTGESAR | |
| SCHEMBL2814868 | 0.80 | PDE7A (0.44) | VCAM1PTGESARALDH1A1LMNA | |
| Water SCHEMBL27993079 | 0.79 | AR (0.52) | ARALDH1A1PDE7A | |
| SCHEMBL11063382 | 0.78 | AR (0.47) | VCAM1ARALDH1A1PDE7A | |
| SCHEMBL1999857 | 0.78 | PDE7A (0.54) | ARALDH1A1LMNAPDE7A | |
| SCHEMBL73860 | 0.78 | VCAM1 (0.70) | VCAM1ALDH1A1LMNA | |
| SCHEMBL11088786 | 0.78 | SLC22A12 (0.51) | VCAM1PTGESARALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102875414-A | Preparation method of 4-amino-2-trifluoromethyl cyanophenyl | CHANGZHOU WATSON FINE CHEMICALS CO LTD | 2013-01-16 | — | — | CN | claimed |
| CN-118666714-A | Purification method of bicalutamide intermediate | 江西金丰药业有限公司 | 2024-09-20 | — | — | CN | disclosed |
| US-11319282-B2 | Diamine compound and method for producing same | LG CHEM, LTD. (KR) | 2022-05-03 | — | — | US | disclosed |
| CN-109415301-B | Diamine compound and method for producing same | 株式会社LG化学 | 2021-08-17 | — | — | CN | disclosed |
| EP-2853532-B1 | 1,2,4-oxadiazole derivatives as allosteric modulators of metabotropic glutamate receptors belonging to group III | INST FARMAKOLOGII POLSKIEJ AKADEMII NAUK (PL) | 2020-12-09 | — | — | EP | disclosed |
| EP-3696165-A1 | PROCESS FOR THE PREPARATION OF 4-HALOPHENOXY-2-TRIFLUOROMETHYL BENZONITRILE | BASF Agro B.V. (NL) | 2020-08-19 | — | — | EP | disclosed |
| EP-3696159-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENOXYPHENYL KETONES | BASF Agro B.V. (NL) | 2020-08-19 | — | — | EP | disclosed |
| EP-3696164-A1 | PROCESS FOR THE PREPARATION OF 4-NITRO-2-(TRIFLUOROMETHYL)-BENZONITRILE | BASF Agro B.V. (NL) | 2020-08-19 | — | — | EP | disclosed |
| EP-3696164-A1 | PROCESS FOR THE PREPARATION OF 4-NITRO-2-(TRIFLUOROMETHYL)-BENZONITRILE | BASF Agro B.V. (NL) | 2020-08-19 | — | — | EP | disclosed |
| US-20190292138-A1 | DIAMINE COMPOUND AND METHOD FOR PRODUCING SAME | LG CHEM, LTD. (KR) | 2019-09-26 | — | — | US | disclosed |
| WO-2009068552-A1 | PIPERAZINYL-SULFONAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2009-06-04 | — | — | WO | disclosed |
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | US | disclosed |
| WO-2004013115-A2 | CARBOXAMIDES, PRODUCTION AND USE THEREOF AS MEDICAMENTS____ | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-02-12 | — | — | WO | disclosed |
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5187167-A | Antitumor agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| US-5081124-A | Amino acid and polyamino acid derivatives, inhibitors of thymidylate synthetase | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| EP-0239362-B1 | ANTI-TUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |
| EP-0239362-A2 | Anti-tumor agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292138-A1 | DIAMINE COMPOUND AND METHOD FOR PRODUCING SAME | DDC, CAD, AOC1 | VCAM1 1345/4885PTGES 1747/4885AR 3530/4885 |
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F2, F11, F12 | VCAM1 947/4885PTGES 899/4885AR 3477/4885 |
| US-11319282-B2 | Diamine compound and method for producing same | DDC, CAD, AOC1 | VCAM1 1345/4885PTGES 1747/4885AR 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.