SCHEMBL23832425

SCHEMBL23832425

N#Cc1ccc(N2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)cc1C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 9/20 0.51
CA12 O43570 3/20 0.51
CA9 Q16790 3/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
PTGES O14684 1/20 0.48
PGR P06401 1/20 0.46
SCN2A Q99250 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30104270 1.00 AR (0.51) ARCA12CA9CA1CA2
SCHEMBL6584691 0.82 CA12 (0.54) ARCA12CA9CA1CA2
SCHEMBL27418761 0.81 AR (0.57) ARPGR
SCHEMBL23832424 0.81 AR (0.52) ARPGR
SCHEMBL2853583 0.80 VCAM1 (0.54) ARPTGES
SCHEMBL21155709 0.76 AR (0.47) ARPTGESPGR
SCHEMBL7036449 0.76 AR (0.55) AR
SCHEMBL11475499 0.75 ALDH1A1 (0.62) CA12CA9CA1CA2
SCHEMBL23832419 0.73 PGR (0.52) ARPGR
SCHEMBL23844244 0.73 AR (0.47) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103470-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIV SOUTHERN CALIFORNIA (US) 2026-04-16 US disclosed
US-12552806-B2 Androgen receptor regulation by small molecule enantiomers UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2026-02-17 US disclosed
US-20240208985-A2 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-06-27 US disclosed
US-20240208985-A2 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-06-27 US disclosed
US-20230133119-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-05-04 US disclosed
US-20230133119-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-05-04 US disclosed
EP-4121044-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-01-25 EP disclosed
WO-2021189051-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2021-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208985-A2 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS AR, SHBG, NR5A1 AR 1/4885CA12 3780/4885CA9 3449/4885
US-20260103470-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS AR, FSHR, GNRHR AR 1/4885CA12 2623/4885CA9 1563/4885
US-20230133119-A1 ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS AR, SHBG, NR5A1 AR 1/4885CA12 3758/4885CA9 3384/4885
US-12552806-B2 Androgen receptor regulation by small molecule enantiomers AR, ADRA1D, ADRA1A AR 1/4885CA12 2335/4885CA9 1523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.