Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538886 | 0.81 | ALOX15 (0.34) | ALOX15CTNNB1GAARORC | |
| SCHEMBL28538887 | 0.81 | ALOX15 (0.34) | ALOX15CTNNB1GAARORC | |
| SCHEMBL28625576 | 0.78 | ALOX15 (0.37) | ALOX15CTNNB1 | |
| SCHEMBL23189671 | 0.77 | SLC6A9 (0.34) | SLC6A9 | |
| SCHEMBL28536649 | 0.77 | RORC (0.33) | ALOX15CTNNB1GAARORC | |
| SCHEMBL28536645 | 0.77 | RORC (0.33) | ALOX15CTNNB1GAARORC | |
| Hydrochloric Acid SCHEMBL23189768 | 0.76 | SLC6A9 (0.33) | SLC6A9 | |
| SCHEMBL29135764 | 0.75 | ALOX15 (0.34) | ALOX15CTNNB1 | |
| SCHEMBL28647956 | 0.75 | USP2 (0.35) | ALOX15CTNNB1 | |
| SCHEMBL28534683 | 0.72 | RORC (0.32) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566901-A | Phenyl-substituted pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112334450-A | Phenyl and pyridyl substituted imidazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-02-05 | — | — | CN | disclosed |